Acne Scarring Removal & Accutane Side Effects Relief

Accutane's Adverse Side Effects on the Skin

The FDA has required Hoffmann-La Roche to revise its label for Accutane many times. The most recent label states: "Many of the side effects and adverse reactions seen in patients receiving Accutane are similar to those described in patients taking very high doses of vitamin A (dryness of the skin and mucous membranes, of the lips, nasal passage, and eyes."

Skin and Appendages: acne fulminans, alopecia (which in some cases persists), bruising, cheilitis (dry lips), dry mouth, dry nose, dry skin, epistaxis, eruptive xanthomas, flushing, fragility of skin, hair abnormalities, hirsutism, hyperpigmentation and hypopigmentation, infections (including disseminated herpes simplex), nail dystrophy, paronychia, peeling of palms and soles, photoallergic/photosensitizing reactions, pruritus, pyogenic granuloma, rash (including facial erythema, seborrhea, and eczema), sunburn susceptibility increased, sweating, urticaria, vasculitis (including Wegener's granulomatosis: see PRECAUTIONS: Hypersensitivity), abnormal wound healing (delayed healing or exuberant granulation tissue with crusting; see PRECAUTIONS: Information for Patients and Prescribers).

Hoffmann-La Roche down-plays the side effects of Accutane by talking about its effect on the skin. They readily admit that it causes skin diseases and/or injuries. Following are just a few of those skin and appendages side effects.

Acne Fulminans

Acne fulminans is a rare and very severe form of acne conglobata associated with systemic symptoms. It nearly always affects males. It is characterized by:

Abrupt onset

Inflammatory and ulcerated nodular acne on chest and back

Severe acne scarring

Fluctuating fever

Painful joints

Malaise (i.e. the patient feels unwell)

Loss of appetite and weight loss

Raised while blood cell count

(Hair Loss - Sometimes Permanent)

Epistaxis
(Nose Bleeds)

Eruptive Xanthomas

Eruptive xanthomas are yellow-orange-to-red-brown papules that are often surrounded by an erythematous halo. They appear in crops on the buttocks, extensor surfaces of the extremities, and flexural creases. Acutely, variable amounts of pruritus and pain occur. A Koebner reaction may be present. Lesions usually resolve spontaneously over weeks and may result in hypertrophic scars. Histologically, foamy macrophages are present in the dermis with an inflammatory infiltrate of lymphocytes and neutrophils.

Eruptive xanthomas can occur in the setting of chylomicronemia and hypertriglyceridemia. (Hypertriglyceridemia is a frequent side effect of Accutane.) This may be due to a primary hyperlipoproteinemia resulting from a genetic deficiency of lipoprotein lipase (Type 1 hyperlipoproteinemia) or familial hyperlipoproteinemia (Type V). Eruptive xanthomas often also occur secondarily in individuals unresponsive to insulin. Insulin is required for the normal triglyceride clearing function of lipoprotein lipase. Whenever insulin deficiency is present, an acquired lipoprotein lipase deficiency exists, which results in impaired clearance of chylomicrons and very-low-density lipoproteins causing the resultant hypertriglyceridemia. Rarely, eruptive xanthomas have been reported with hypothyroidism, nephrotic syndrome, and von Gierke's glycogen storage disease. They have been noted also after ingestion of alcohol, glucocorticoids, estrogens, and retinoids.

Other features of hyperlipidemia often noted in patients with eruptive xanthomas include lipemia retinalis, hepatosplenomegaly, and abdominal pain. The abdominal pain may be secondary to intestinal ischemia from increased blood viscosity, stretching of organ

Hirsutism
(Increased Hair Growth Even in Women)

Vasculitis Including Wegener's Granulomatosis

Wegener's Granulomatosis (WG) is a rare form of vasculitis; that is, a disease characterized by inflammation of the walls of the blood vessels. This inflammation can result in damage to vital organs of the body by restricting blood flow to those organs. WG normally begins as a localized granulomatous inflammation of the nasal mucosa (lining) and lung tissue, and usually progresses into generalized necrotizing (gradual degeneration) granulomatous (tumor-like) inflammation of the blood vessels. WG is an autoimmune disease, meaning the body's immune system attacks its own body tissue.

Although vasculitic diseases can result in damage to any organ system, WG primarily affects the respiratory tract (sinus, nose, trachea, and lungs) and the kidneys, and may involve the joints, eyes, ears, and skin. Patients who do not have renal (kidney) involvement are described as having Limited Wegener's. This disorder occurs equally in males and females and can occur at any age, but usually in middle age. For more information, please visit, Wegener's Granulomatosis Association

Relief of the effects of Accutane on the skin

Acne scarring can be prevented and healed while you are on Accutane, and Acuttane's side effects can be relieved. Acne produces multiple skin injuries (inflammatory infections) that place heavy demands upon the skin's components. Areas with recurrent acne infections caused by moderate or severe acne frequently develop deficiencies of essential ingredients, impairing the skin's ability to defend itself and heal efficiently.

Acne infections destroy collagen and elastin fibers, sever the microvascular system and damage and kill cells. When healing occurs, normally after a long time if acne injuries are not properly treated, a scar is left in the skin. The normal functional tissue (skin) is replaced by connective tissue (scar).

BIOSKINCARE™ is a cream that absorbs quickly and helps to prevent scarring and speeds up the regeneration of skin cells. It is made from a substance gathered from live creatures (Snails, without any harm to them). The natural substance is a complex compound that combines natural antimicronbial peptides that fight acne infection and biologically active skin regenerating peptides that boost the proliferation of fibroblasts which give rise to new connectiuve tissues collagen and elastin. It also vanishes red marks, shrinks scar tissues and prevents and repairs scarring.

It also contains and boosts the prodution from within the bsal layer of the skin of glycosaminoglycans the water holding carbohydrate molecules that restore the moisturizing capacity of a healthy skin.

The natural antimicrobial action of BIOSKINCARE™ is very effective against skin infections and without the pitfalls of pharmaceutical antibiotics or the side effects of harsh chemicals. BIOSKINCARE™ also helps to get rid of the chemical inflammatory promoters (i.e. interleukin-6, hydrogen peroxide, histamines, bacterial toxins) that are significantly increased by acne infection..

Pitted, ice pick scarring can also be improved permanently with the disciplined application of BIOSKINCARE™. Results are noticeable within a few weeks when used twice a day. Full results can take several months depending on how deep and old is the scarring.

BIOSKINCARE™ can be used to heal acne scars or acne scarring in conjunction with retinoids (isotretinoin: Accutane®, Roaccutane, or Retin A, Differin gel, etc.) or in conjunction with oral systemic antibiotics used to stop severe acne infections. It also acts as a natural antibacterial for use on the skin without the pitfalls of pharmaceutical antibiotics.

BIOSKINCARE™ does not interfere or interact with retinoids (isotretinoin: accutane, roaccutane, or with Retin A, Differin, etc.) prescribed to reduce your sebum production. Nor does it interfere with systemic antibiotics (such as Tetracycline or Minocycline) or with topical chemical antiseptic products that fight acne bacteria (such as benzoyl peroxide or salicilyc acid).

Understanding the process of skin renewal and repair of acne scarring

The key to skin renewal is a process where (1) the skin is irritated or slightly damaged by exfoliating agents such as the enzymes contained naturally in BIOSKINCARE™) or mildly damaged by other procedures ("sanding" by dermabrasion or burning by laser). This is followed by (2) a natural rebuilding of the skin that removes imperfections, rebuilds collagen and elastin fibres that tighten skin, and increases the amount of glycosamoinoglycans, the moisture-holding proteins that give skin its firmness.

The stronger the exfoliation or skin damage, the stronger is the skin rebuilding action. Unfortunately, strong exfoliation causes strong skin irritation with itching, burning, and pain. And the results of laser resurfacing or dermabrasion depend on the skills of the practician.

THE ROLE OF BIOSKINCARE™

However to get good results with any skin renewal procedure it is IMPERATIVE skin healing progresses at rapid pace. Here is where BIOSKINCARE™ plays a role, and it is recommended even for use after dermabrasion or laser re-surfacing.

BIOSKINCARE™, as the snail's slime it is made off contains activators of removal of damaged skin cells and skin regenerating accelerators. The skin regeneration accelerators are special proteins and peptides (amino-acid chains) that signal the body to start reproducing human skin cells as quickly as for the repair of the snail's skin. Part of its effect is decreasing the "glue" that holds dead cells on the surface of the skin by reducing cell cohesion in lower levels of the stratum corneum. This triggers an increase in cell renewal. And helps the dead cells to slough off (desquamation), speeds skin turnover, and brings to the surface a layer of smoother, softer skin. It also removes skin lesions, and restores the skin firmness, elasticity, and internal moisture-holding properties.

When BIOSKINCARE™™ is used as a long term skin care routine (2 to 4 months) it may be as good as a short term strong chemical peel or a skilled dermabrasion or laser-resurfacing procedure. Results may be more noticeable in the beginning, when the outer layer of damaged skin is peeled off. Then the repair process continues within the skin follicles at a less noticeable pace.

BIOSKINCARE™ also acts within the skin follicles, on the surface and inside the dermis, to restore a normal and healthy skin with normal pigment production. You must also apply a sunscreen or wear protective clothing to prevent darkening from further sun exposure.

The first effect is a softness of your skin, the ultimate healing is when new "invisible hair" called “lanugo” start coming out of the restored hair follicles where the skin was once damaged. This process can take as long as 4 to 12 months for damaged skin and old scars.

Get rid of scars, stretch marks and all types of skin blemishes, while moisturizing, protecting, repairing and renewing your skin with BIOSKINCARE

Dissolves scar tissues and releases the aminoacids and other components in them for the reproduction of fibroblasts which give rise to new connective tissues and glycosaminoglycans -the molecules that deeply moisturize, firm skin and give it strenght and capacity to withstand over-stretching. It also replenishes the lipid barrier of the skin and triggers the regeneration of damaged cells while preventing and removing acne scars, keratosis, psoriasis scales and all types of skin blemishes.

 

Made in the USA. One Month's supply 50 grams = 1.76 oz

50 Gram Bottle: $59.98

Save at least 20% off price & save on domestic or world wide shipping costs
when you order more than one month's supply

Discount Price Two Bottles: $37.45 each, at checkout within our secure shopping cart.
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Natural Acne Gel, Rosacea Remedy & Scar Healing

This gel is an oil free product and is a natural remedy for acne, rosacea, and scar healing with moisturizing seaweed extracts. Best for people with very oily skin conditions. All our products are safe for children, moms-to-be and breast fedding mothers.

 

Made in the USA. One Month's supply 50 grams = 1.76 oz

50 Grams in One Airless Pump Bottle: $49

 

 

Save at least 20% off price & save on domestic or world wide shipping costs
when you order more than one month's supply

Discount Price Two Bottles: $39.20 each, at checkout within our secure shopping cart.
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Ultra Exfoliate Your Skin with BIOSKINEXFOL

A home microdermabrasion cream with high quality micro-crystals, the same professionals use to breakdown hard, rough and old scar tissues, and allow for a deeper penetration of our exclusive all natural skin moisturizing and regeneration complex contained in the microdermabrasion cream. For ice-pick acne scars and for old and rough scars and actinic keratosis scales. Not for keloids.

Microdermabrasion Benefits

Made in the USA. Two to Three Month's supply 120 grams = 4.23 oz

120 Gram Bottle: $79